Description
GHK-Cu Copper Peptide is a naturally occurring copper-binding tripeptide that has become one of the most extensively investigated molecules in regenerative biology and extracellular matrix research. First identified in human plasma, the peptide consists of the amino acid sequence Gly-His-Lys (GHK) coordinated with a copper(II) ion, forming a biologically relevant complex that researchers continue to investigate across multiple areas of molecular biology and peptide science.
In laboratory settings, GHK-Cu is widely studied for its interaction with copper-dependent cellular processes, peptide signaling pathways, extracellular matrix regulation, and gene expression associated with connective tissue biology. Scientific investigations have also explored its relationship with collagen synthesis, elastin production, matrix metalloproteinase regulation, antioxidant defense systems, and cellular responses to oxidative stress under controlled experimental conditions.
Appex Peptide Lab manufactures GHK-Cu Copper Peptide using carefully controlled synthesis and purification methods to ensure exceptional purity, structural integrity, and batch consistency. Each production lot undergoes independent analytical verification before release, providing researchers with confidence in product quality and reproducibility.
Trusted by universities, biotechnology companies, pharmaceutical organizations, cosmetic science laboratories, and tissue engineering researchers throughout the United States, Canada, and Australia, GHK-Cu Copper Peptide supports advanced laboratory investigations requiring dependable research materials.
Key Research Highlights
- Premium research-grade GHK-Cu Copper Peptide
- Naturally occurring copper-binding tripeptide complex
- High-purity lyophilized formulation
- Copper coordinated in defined peptide complex
- Third-party laboratory tested
- HPLC purity verification
- Certificate of Analysis (COA) available
- Batch-tested for consistency
- Suitable for extracellular matrix and peptide signaling research
- Secure laboratory packaging
- Fast shipping to the USA, Canada, and Australia
Why Researchers Choose This Product
Researchers require analytically verified peptide standards capable of delivering reproducible performance across diverse laboratory studies. GHK-Cu Copper Peptide from Appex Peptide Lab is manufactured with scientific precision and quality assurance at every stage.
Researchers choose this product because it offers:
- High analytical purity
- Verified copper-peptide complex
- Excellent batch-to-batch consistency
- Independent third-party laboratory verification
- Stable lyophilized formulation
- Transparent analytical documentation
- Reliable peptide identity confirmation
- Research-grade manufacturing standards
- Trusted by biotechnology and academic laboratories
- Suitable for advanced molecular biology investigations
Research Applications
Extracellular Matrix Research
Laboratory investigations examining collagen organization, extracellular matrix turnover, and connective tissue biology.
Copper-Dependent Cellular Signaling
Studies exploring molecular pathways regulated by copper-peptide interactions and intracellular signaling networks.
Peptide Chemistry
Research involving peptide stability, copper coordination chemistry, and structure-function relationships.
Molecular Biology
Experimental studies evaluating gene expression, protein regulation, and intracellular communication associated with peptide signaling.
Cell Culture Research
Suitable for in vitro investigations involving fibroblast biology, extracellular matrix proteins, and cellular physiology.
Oxidative Stress Research
Laboratory studies examining antioxidant-related molecular pathways and cellular responses to oxidative conditions.
Tissue Engineering
Research supporting investigations into scaffold biology, connective tissue remodeling, and biomaterial interactions.
Cosmetic Science Research
Experimental studies exploring peptide interactions relevant to skin biology, extracellular matrix organization, and cellular signaling mechanisms.
Product Specifications
| Specification | Details |
|---|---|
| Product Name | GHK-Cu Copper Peptide |
| Alternative Name | Copper Tripeptide-1 |
| Available Sizes | 50 mg, 100 mg |
| Purity | ≥98% (HPLC Verified) |
| Molecular Formula | C₁₄H₂₄CuN₆O₄ |
| Molecular Weight | Approximately 401.9 g/mol |
| CAS Number | 89030-95-5 |
| Appearance | Blue to blue-violet lyophilized powder |
| Solubility | Soluble in laboratory-grade water and appropriate aqueous research buffers |
| Storage Conditions | Store at -20°C for long-term preservation. Protect from light, humidity, and repeated freeze-thaw cycles. |
| Sequence | Gly-His-Lys-Cu (GHK-Cu) |
Mechanism of Action
Within laboratory research, GHK-Cu Copper Peptide is investigated as a biologically active copper-binding tripeptide capable of participating in multiple cellular signaling pathways associated with extracellular matrix regulation and peptide-mediated molecular communication. The peptide forms a stable coordination complex with copper(II), allowing researchers to examine how peptide-bound copper influences biochemical processes within controlled experimental environments.
Scientific investigations have demonstrated that GHK-Cu interacts with numerous cellular pathways involved in connective tissue biology, including regulation of extracellular matrix proteins, matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs), and intracellular transcriptional responses. Researchers continue to investigate how these interactions influence peptide signaling networks, protein synthesis, and cellular homeostasis.
Experimental studies have also examined GHK-Cu in relation to fibroblast activity, collagen-associated protein expression, elastin regulation, glycosaminoglycan production, and copper-dependent enzyme systems. Additional laboratory investigations explore molecular mechanisms associated with antioxidant responses, oxidative stress signaling, mitochondrial function, and cellular adaptation to environmental stressors.
At the genomic level, GHK-Cu has been investigated for its ability to influence patterns of gene expression involved in extracellular matrix remodeling, cellular differentiation, and tissue organization under controlled laboratory conditions. Researchers also continue to evaluate its interaction with signaling pathways involved in cellular communication, protein regulation, and peptide pharmacology.
Because GHK-Cu functions as a naturally occurring copper-peptide complex rather than a receptor-selective agonist, ongoing scientific investigations focus on understanding its broad molecular activity across peptide chemistry, regenerative biology, biomaterials research, molecular pharmacology, and cellular physiology. These studies remain strictly experimental and are intended solely to expand scientific knowledge rather than support therapeutic or clinical applications.
For research use only. Not intended for human consumption or clinical use.





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